How to manage human biospecimens in clinical research – Central BioHub

 

The term "human biological samples" refers to any substances from the human body collected for diagnosis, treatment or research. It is  referred to as "human biospecimens" or "human biosamples." It comprises of but is not restricted to, blood, urine, sputum, faeces, saliva, organs, teeth, hair, tissues, cell lines, DNA, bones, and other materials that are gathered during any clinical or laboratory procedure, including biopsies, surgery, etc

Best practices for managing human samples for research

It is paramount that human bio specimens must be handled carefully in all biomedical research and diagnostic disease research areas. The risk of infection for the person handling the samples cannot be ruled out because they come from healthy donors who self-report as being in good health or from patient populations. To prevent direct contact and cross-contamination, every human sample used in clinical trials is treated as potentially infectious and subject to special regulations for handling them during research. At the same time, human samples are highly perishable and can also lose their integrity and quickly deteriorate over time. Therefore, human samples or any biological samples should be appropriately stored under enumerated cryogenic conditions for long-term preservation.

Additionally, national regulatory frameworks must be complied with for the efficient management of biological samples and related data for research. It mainly safeguards the donors' or patients' rights and interests; this regulation regulates how human samples are handled and managed for research projects. Additionally, any research project using human biosamples must have a detailed protocol outlining the research project and the justification for using human specimens, approved by an ethical committee and IRB.

A detailed and precise informed consent form that the donor has properly read (or explained), understood, and duly signed must be provided to obtain the donor's full consent before collecting the samples. The use of the samples in the research must also be specified in the informed consent form. Additionally, a trained technician should collect the samples while working under the supervision of a medical professional to ensure that the human donors are not in danger. Finally, the samples should be carefully handled in accordance with biobanking regulations and safety standards before being stored for research in accredited human biobanks. To verify compliance with the law and check the quality of human research samples, routine audits and quality control must be carried out. Learn more about the use of human biological specimens for research: https://centralbiohub.de/blogs/human-samples

Central BioHub presents millions of human samples online. 

As a well-known online human biospecimen marketplace, Central BioHub helps in the acquisition of biospecimens quicker and more conveniently than ever before. It connects world-class biobanks and researchers, contract research organisations, and non -profitable research organisations worldwide by bringing them together at a unique online platform.

We leverage our expertise in bringing more than 800,000 highly characterised human biospecimens and disease-state biospecimens from certified biobanks and biorepositories, making them easily procurable online. It includes human serum and plasma samples, whole blood, tissue, PBMC, urine, swabs, CSF, and additional human samples intended only for research. Check out the inventory here. https://centralbiohub.de/biospecimens/


Order your clinical research samples from Central BioHub immediately to prepare for a game-changing discovery; we're your go-to source for high-quality human biomaterials for research.

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