CentraBiohub

  Human Specimens and Biobanks  Human specimens are natural substances from the human body that are gathered and preserved for disease diagnosis and scientific investigation. It is also known as human biomaterials, human biospecimens, or human biosamples. It includes human organs, tissues, cells, DNA, body fluids, teeth, hair, skin, and other components legally and morally collected from patients and donors. These human specimens are precious and widely used in biomedical research and in developing novel therapeutics and diagnostics to manage and treat diseases. All human specimens are one-of-a-kind and unrepeatable elements. Human samples can give researchers a detailed account of the patient's journey in life. Studies on human samples from various people support translational and precision medicine. Research on various genetically diverse human bio specimens also helps to comprehend disease patterns and epidemiological studies. As a result, leftover human samples and clinica...

  Production of PBMCs in the body? The production of human Peripheral Blood Mononuclear Cells starts with haematopoietic stem cells in the bone marrow through a process called haemopoiesis. During this process, the cells differentiate into two distinct lineages known as myeloid and lymphoid. PBMCs are then released into the bloodstream to enhance immunity, consisting of rounded single-nucleated lymphoid cells and specific myeloid cells. These cells are crucial in fighting bacteria, viruses, fungi, and other external threats to the human body, serving as the immune system's primary defence mechanism. As our bodies first line of defence, PBMCs play a critical role in maintaining good health. Application of Human PBMC cells in Medical Research Peripheral Blood Mononuclear Cells (PBMCs) are considered to be the cornerstone and regulatory element of the human immune system. In recent years, blood samples containing PBMCs have been widely used in various biomedical research fields, inclu...

  What exactly is human plasma? Human plasma is the liquid component of blood essential for delivering blood components throughout the human body. Plasma makes up to 55% of blood in the human body , making it the most significant element. Plasma is the clear yellow or straw-coloured intercellular liquid derived after isolating blood cells from the liquid fraction of blood. It comprises 10% dissolved proteins, hormones, enzymes, vitamins, ions, waste materials, and 90% water. Plasma's main function is to transport blood and numerous biological components like hormones, proteins, and nutrients all over the body. In addition, it detoxifies or gets rid of nitrogenous waste products that come from cell metabolism. Plasma is also vital for maintaining the human body's homeostasis since it contains many crucial proteins that keep the blood's osmotic pressure constant. These plasma proteins are fibrinogen, globulin, albumin, coagulation factor, antibodies, and coagulation factor. T...

  Human pregnancy is divided into three trimesters, and the 2nd trimester lasts from 13 to 27 weeks after conception. During this phase, significant changes occur in pregnant women as the uterus grows rapidly, increasing the size of the abdomen. In addition, during the second half of this phase, the musculoskeletal system of the unborn baby develops, and the mother can feel the baby's movements. Moreover, women tend to experience increased energy levels during the 2nd trimester, which is why it is often referred to as the "golden period" of pregnancy. Here are some tips to help prevent complications during the second trimester weeks:  Avoid sleeping on your stomach; instead, try sleeping on your left side. Do not self-medicate or take over-the-counter medications without consulting your healthcare provider. Avoid sitting in one position for long periods. Do not cross your legs while sitting. Avoid strenuous exercise and opt for moderate physical activity. Try to manage st...

  Despite the availability of effective chemotherapeutic drugs and cutting-edge diagnostic tools for the treatment and diagnosis of cancer, the incidence of various cancers is rising alarmingly across the globe. In 2020, there were 19.3 million new cases of cancer and 10.0 million deaths from oncological diseases, excluding nonmelanoma skin cancer, according to reports on the global burden of cancer by the International Agency for Research on Cancer captured using GLOBOCAN 2020. Research on various aspects of cancer is being intensified to find a long-term cure for the illness and a way to prevent cancer from ever occurring.  Tips to Collect Cancer Tissue Samples  Human biospecimens from cancer patients of different ages, genders, ethnicities, and races are always needed for oncology research. The precise pathophysiology of cancer can be understood, its susceptibility can be measured, and the risk factors that contribute to it can be identified through researching cancer ...

  Facts About Pregnancy Trimesters Pregnancy is a significant stage in a woman's life that brings physical and psychological changes to prepare for the arrival of a newborn. It's essential to thoroughly understand the different stages of pregnancy to provide better care and avoid complications. A normal full-term human pregnancy lasts for 40 weeks and is divided into three trimesters: the 1st trimester, 2nd trimester, and 3rd trimester. The 1st trimester is the most critical and lasts from 0 to 13 weeks, during which the baby's organs and body structure develop. Additionally, the mother may experience various symptoms such as nausea, vomiting, breast tenderness, sore nipples, fatigue, etc. Extra care during this period is crucial to prevent miscarriage and other complications. The 2nd trimester of pregnancy lasts from 14 to 26 weeks and is often referred to as the 'golden stage.' Most of the early pregnancy symptoms disappear, and the mother may feel the unborn baby...