Syphilis- Diagnosis, Symptoms, and Treatment.

 

What exactly is Syphilis?

Syphilis is one of the most common sexually transmitted diseases (STDs) affecting millions of people across the globe. It is caused by a spirochete called Treponema pallidum, a small, spiral-shaped, highly contagious bacterium belonging to the spirochete family. Unprotected sexual contact with an infected partner is the most common method of transmission of Syphilis. It can also spread through nonsexual contact, blood transfusion, etc. Moreover, a mother infected with Syphilis can transmit the infection to her newborn child. An untreated syphilis infection can result in organ failure and death unless it is treated immediately.

What are the ways to Diagnose Syphilis Disease?

The preliminary diagnosis of Syphilis is determined by carefully examining the painless indurated lesions known as syphilis chancre or syphilis rashes, particularly on the genital organs in both males and females. In the advanced stages of the disease, the patient may experience other syphilis symptoms, such as flu-like symptoms, rashes, lesions, lymphadenopathy, and infections of many organs. When considering the aforementioned syphilis symptoms, a skilled doctor can determine a medical diagnosis. However, a number of syphilis testing methods are used to confirm an illness. Darkfield microscopy of the Treponema pallidum bacteria is one among them. Besides, biomarkers that are released during treponemal infection are tested on syphilis specimens by nontreponemal serological tests like VDRL and RPR. Comparatively, treponema pallidum antibodies, such as IgG, IgM, and to a lesser extent IgA, which is specific for syphilis infection, are found by treponemal assays such FTA-ABS, TP-PA, and other EIAs.

Can Syphilis Disease be Treated? 

Yes, infection with Syphilis is treatable and ultimately curable. The mainstays in treating the condition and preventing future damage, however, depend on the early detection and initiation of the right choice of antibiotics in different syphilis stages. Effective treatment for Syphilis often involves the administration of a single dose of intramuscular benzathine penicillin G along with parenteral penicillin G, procaine penicillin G, and aqueous crystalline penicillin G. In situations where a person is allergic to penicillin, Azithromycin is administered. Due to the fact that 80% of the syphilis bacteria are already resistant to this antibiotic, according to a US study published in 2018, it is essential to conduct research on new powerful antibiotics.

Discover a Wide Range of Syphilis Specimens for Research

Central BioHub, a company with European roots, offers human biospecimens ideal for life science research, such as diagnostic, clinical, therapeutic, or drug discovery. To give the finest patient care possible, we, as biospecimen suppliers, encourage research that improves current medical care procedures.

To hasten the study of infectious diseases around the world, Central BioHub provides a variety of top-quality research biospecimens that are obtained from syphilis patients all over the world. It has partners with biorepositories at Central BioHub to bring millions of banked samples available for research. We offer blood-derived samples such as serum and plasma samples collected from patients examined for anti-syphilis IgG and anti-syphilis IgM, as well as other syphilis testings. All syphilis blood samples are readily available in stock and procurable online. Check out the sample inventory for more details on syphilis biospecimens: https://centralbiohub.de/biospecimens/sexually-transmitted-diseases/syphilis

Besides, Central BioHub also offer syphilis infection samples from both pregnant and non-pregnant patients in their bio inventory, along with accurate annotations of all clinical evaluation reports. Be hasty! For high-quality and affordable syphilis samples for research, check out their online inventory.